CasNo：23111-00-4
Product Name:Nicotinamide riboside chloride
Molecular Formula:C11H15ClN2O5
Purity:99%
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1.What is the Nicotinamide riboside chloride ?
Nicotinamide riboside is involved in nicotinate and nicotinamide metabolism. Nicotinamide riboside was originally identified as a nutrient in milk and later discovered to be a NAD(+) precursor.Nicotinamide riboside (NR) is a naturally occurring vitamin B-3 present in the human diet that acts as an NAD+ precursor and is suggested to improve mitochondrial function and insulin sensitivity. NR acts via activation of the NAD+-dependent sirtuin enzyme family, thereby regulating oxidative metabolism. In vitro experiments of NR supplementation have shown its successful NAD+-restoring capability and subsequent increased oxidative gene expression in skeletal muscle cells. Results from in vivo mouse models have shown improvements in insulin sensitivity and oxidative energy metabolism, including enhanced metabolic flexibility, increased aerobic exercise capacity, and indications of improved mitochondrial biogenesis.
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- 109527-15-3
5’,3‘,2’-tri-O-acetyl-1-β-D-ribofuranosylnicotinamide chloride
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- 23111-00-4
3-carbamoyl-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium (β-D-nicotinamide riboside)
| Conditions | Yield |
|---|---|
|
With ammonia; In methanol; at -3 ℃; for 24h; Temperature;
|
89.3% |
|
With ammonia; In methanol; at -15 - -10 ℃; Temperature; Reagent/catalyst;
|
82% |
|
With ethanol; ammonia; at 10 - 20 ℃; for 3h;
|
78% |
|
With methanol; ammonia; at -5 - 0 ℃; for 12h; Large scale;
|
78% |
|
With hydrogenchloride; In methanol; ethanol; at 20 ℃; for 4h;
|
64% |
|
With ammonia; In methanol; at 0 ℃; for 14h; Large scale;
|
60% |
|
With methanol; ammonia;
|
|
|
With hydrogenchloride; In methanol; for 12h; Reagent/catalyst; Solvent; Sealed tube;
|
|
|
With methanol; propylamine; at -5 ℃; for 22h; Temperature;
|
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![1-[(2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofur-2-yl]-1,4-dihydropyridine-3-carboxamide](/upload/2023/8/86bbf149-5ef7-4113-8112-61669a83cefe.png)
- 19132-12-8
1-[(2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofur-2-yl]-1,4-dihydropyridine-3-carboxamide
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- 23111-00-4
3-carbamoyl-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium (β-D-nicotinamide riboside)
| Conditions | Yield |
|---|---|
|
With ammonium chloride; In water; at 20 ℃; for 1h; Solvent;
|
100% |
|
With 5%-palladium/activated carbon; ammonium chloride; In isopropyl alcohol; at 20 ℃; for 20h; under 1500.15 Torr; Reagent/catalyst; Temperature; Solvent; Pressure; Green chemistry;
|
89% |
2.What is the CAS number for Nicotinamide riboside chloride ?
The CAS number of Nicotinamide riboside chloride is 23111-00-4.
More information of Nicotinamide riboside chloride 23111-00-4 are:
|
CAS Number |
23111-00-4 |
|
HS CODE |
2938909090 |
|
PSA |
116.89000 |
|
LogP |
-4.61120 |
3.What are another words for Nicotinamide riboside chloride ?
Synonyms for Nicotinamide riboside chloride 23111-00-4:Nicotinamide riboside chloride;3-Carbamoyl-1-beta-D-ribofuranosylpyridinium chloride
4.What is the molecular formula of Nicotinamide riboside chloride?
The chemical formula of Nicotinamide riboside chloride is C11H15N2O5.Cl which containing 11 Carbon atoms,15 Hydrogen atoms,2 Nitrogen atoms,1 Oxygen atoms and 1 Chlorine atoms,and the molecular weight of Nicotinamide riboside chloride is 290.703.
5.What is Nicotinamide riboside chloride (23111-00-4) used for?
Nicotinamide Riboside Chloride is the chloride salt form of nicotinamide riboside(NR).NR is a new form pyridine-nucleoside of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide(NAD) or NAD+ . Nicotinamide riboside chloride is a crystal form of Nicotinamide riboside (NR) chloride. Nicotinamide riboside chloride increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities. Nicotinamide riboside chloride is used in dietary supplements.
Relevant articles related to Nicotinamide riboside chloride:
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Article |
Source |
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Preparation method β - nicotinamide ribose chloride |
- Paragraph 0039; 0078; 0082-0098, (2021/11/10) |
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NMN intermediate NR chloride synthesis method |
- Paragraph 0053; 0059-0061; 0068-0069, (2021/05/29) |
6.Buy Nicotinamide riboside chloride with the best price .
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