CasNo：112809-51-5
Product Name:Letrozole
Molecular Formula:C17H11N5
Appearance:white to off-whitecrystalline powder
Purity:99%
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1.What is the Letrozole ?
white to light yellow crystal
Letrozole (trade name: Femara) is an orally active nonsteroidal aromatase inhibitor. As a competitive inhibitor of the aromatase, Letrozole inhibits the conversion of androgens to estrogen (estrogen stimulates breast tissues and breast cancer reoccurrence) and gonadal steroidogenesis. It can be used for the treatment of breast cancer that is hormonally-responsive or has an unknown receptor status in postmenopausal women. Besides this, Letrozole also has some off-label use such as ovarian stimulation, pretreatment of termination of pregnancy, treatment of gynecomastia, treatment of endometriosis, and promoting spermatogenesis for male patients of nonobstructive azoospermia.
2.What is the CAS number for Letrozole ?
The CAS number of Letrozole is 112809-51-5.
3.What are another words for Letrozole ?
Synonyms for Letrozole 112809-51-5:4,4'-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile
4.What is Letrozole (112809-51-5) used for?
Letrozole has been used:in organoid growth assay to determine its inhibitory capacity(48) to investigate steroid receptor coactivator-1 (SRC-1) mediated endogenous estrogen regulation of hippocampal PSD-95(49) to determine its effects on tumor-induced hyperalgesia(50) for hormonal manipulation in rats(51) to study its effects on lipocalin-2 (Lcn2)(52) to determine its effects on mechanical hyperalgesia and aromatase expression(53)
InChI:InChI=1/C17H11N5/c18-9-13-1-5-15(6-2-13)17(22-12-20-11-21-22)16-7-3-14(10-19)4-8-16/h1-8,11-12,17H
Relevant articles related to Letrozole:
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Article |
Source |
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A novel process for the synthesis of substantially pure Letrozole |
Suman,Vijayabhaskar,NageswaraRao,Syam Kumar,VenkateswaraRao , p. 1 - 8 (2019) |
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Nickel-Catalyzed Cyanation of Aryl Thioethers |
Delcaillau, Tristan,Woenckhaus-Alvarez, Adrian,Morandi, Bill supporting information, p. 7018 - 7022 (2021/09/13) |
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Nickel-Catalyzed Reversible Functional Group Metathesis between Aryl Nitriles and Aryl Thioethers |
Delcaillau, Tristan,Boehm, Philip,Morandi, Bill supporting information, p. 3723 - 3728 (2021/04/07) |
5.Buy Letrozole with the best price .
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