CasNo：2894-61-3
Product Name:Bromonordiazepam
Molecular Formula:C15H11 Br N2 O
Purity:99%
Top Purity Buy Quality Bromonordiazepam 2894-61-3 Fast Shipping
- Molecular Formula:C15H11 Br N2 O
- Molecular Weight:315.169
- Vapor Pressure:8.13E-09mmHg at 25°C
- Melting Point:220-221 °C(Solv: ethyl ether (60-29-7))
- Boiling Point:464.8°Cat760mmHg
- PKA:11.72±0.70(Predicted)
- Flash Point:234.9°C
- PSA：44.95000
- Density:1.51g/cm3
- LogP:2.75930
7-bromo-5-phenyl-1,2-dihydro-2H-1,4-benzodiazepin-2-one(Cas 2894-61-3) Usage
|
Description |
Bromonordiazepam is the active metabolite of of the Soviet developed Gidazepam. Bromonordiazepam is closely related is to Diazepam in structure, has a very long half life and is exceptionally anxiolytic with limited non-therapeutic potential. |
|
Uses |
7-Bromo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one inhibits HIV-1 reverse transcription. |
|
Application |
Desalkylgidazepam is an analytical reference standard categorized as a benzodiazepine metabolite.Desalkylgidazepam is a metabolite of gidazepam. This product is intended for research and forensic applications. |
InChI:InChI=1/C15H11BrN2O/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h1-8H,9H2,(H,18,19)
2894-61-3 Relevant articles
Facile and efficient one-pot protocol for synthesis of 5-phenyl-1,4- benzodiazepine-2-one derivatives
Safaei-Ghomi, Javad,Hatami, Alireza
, p. 297 - 302 (2008)
Several new derivatives of 5-pheny-1,4-b...
Structure-Activity Relationship Studies of Retro-1 Analogues against Shiga Toxin
Abdelkafi, Hajer,Michau, Aurélien,Pons, Valérie,Ngadjeua, Flora,Clerget, Alexandra,Ait Ouarab, Lilia,Buisson, David-Alexandre,Montoir, David,Caramelle, Lucie,Gillet, Daniel,Barbier, Julien,Cintrat, Jean-Christophe
, p. 8114 - 8133 (2020/09/21)
High-throughput screening has shown that...
Retro-1-oligonucleotide conjugates. Synthesis and biological evaluation
Agramunt, Jordi,Pedroso, Enrique,Kreda, Silvia M.,Juliano, Rudolph L.,Grandas, Anna
, (2019/02/10)
Addition of small molecule Retro-1 has b...
COMPOUNDS WHICH HAVE A PROTECTIVE ACTIVITY WITH RESPECT TO THE ACTION OF TOXINS AND OF VIRUSES WITH AN INTRACELLULAR MODE OF ACTION
-
, (2016/04/19)
The subject matter of the present invent...
Synthesis, Chiral Separation, Absolute Configuration Assignment, and Biological Activity of Enantiomers of Retro-1 as Potent Inhibitors of Shiga Toxin
Abdelkafi, Hajer,Michau, Aurélien,Clerget, Alexandra,Buisson, David-Alexandre,Johannes, Ludger,Gillet, Daniel,Barbier, Julien,Cintrat, Jean-Christophe
supporting information, p. 1153 - 1156 (2015/07/07)
The Shiga toxin (Stx) family is composed...
2894-61-3 Process route
-
-
2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one
-
![7-bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one](/upload/2023/8/9b1387ad-3717-4749-a4bc-0a0c18856361.png)
-
2894-61-3
7-bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
| Conditions | Yield |
|---|---|
|
With
sulfuric acid; bromine;
In
acetic acid;
at 20 ℃;
for 48h;
|
90% |
|
With
sulfuric acid; bromine;
In
acetic acid;
|
65.9% |
-
-
56-40-6,18875-39-3,25718-94-9
glycine
-
-
34099-70-2
7-bromo-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione
-
-
612527-22-7
C17H14BrN3O2
-
-
2894-61-3
7-bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
| Conditions | Yield |
|---|---|
|
With
water; sodium carbonate;
In
ethanol;
for 5h;
Heating / reflux;
|
67% |
2894-61-3 Upstream products
-
100-97-0
hexamethylenetetramine
-
70890-58-3
5-Bromo-2-(chloroacetamido)benzophenone
-
2898-08-0
2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one
-
39859-36-4
2-amino-5-bromobenzophenone
2894-61-3 Downstream products
-
612525-95-8
7-trimethylsilylacetyleno-5-phenyl-1,3-dihydrobenzo[e]-1,4-diazepin-2-one
-
256234-99-8
1-methyl-7-trimethylsilylacetylenyo-5-phenyl-1,3-dihydrobenzo[e]-1,4-diazepin-2-one
-
2893-99-4
7-bromo-4-oxy-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one
-
1072906-66-1
C24H17BrF2N2O3
![6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine, 2-bromo-4-(2-fluorophenyl)-9-methyl-](/upload/2023/8/3f84cf9b-5622-4199-b521-5e4ae6fd5d64.png)
